ACTH versus corticosteroid in infantile spasms: a literature review

Background: Infantile spasms (IS) represent an age-specific epileptic disorder of infancy and early childhood. Children with infantile typically exhibit along the electroencephalographic (EEG) pattern known as roceededica. Although rare, 1.6 to 4.5 per 10,000 live births, IS is a significant because association developmental delay or regression, high mortality rate, refractoriness conventional antiseizure medications, responsiveness hormonal therapy. Genetic variants acquired factors such hypoxic-ischemic injury, infections, structural abnormalities brain, are some insults that associated IS.